Tai-Chung TsengDoctor

Dr. Tai-Chung Tseng is currently an Associate Professor of Internal Medicine and an attending physician in the Department of Medical Research at National Taiwan University Hospital. His research interests are primarily focused on biomarkers and immune mechanisms of hepatitis B virus (HBV), as well as immunology research related to hepatocellular carcinoma (HCC). Dr. Tseng has published numerous papers on liver disease in renowned national and international journals. In recent years, he has continued to explore the relationship between HBV genotypes and liver cancer risk markers, contributing significantly to academic conferences in this field.

  • Publications 
    1. Tseng TC, Hosaka T, Liu CJ, et al. HBcrAg-based risk score performs better than the HBV DNA-based scores for HCC prediction in grey zone patients who are HBeAg-negative. JHEP Rep 2024;6:100956.
    2. Tseng TC, Chiang C, Liu CJ, et al. Low Hepatitis B Core-Related Antigen Levels Correlate Higher Spontaneous Seroclearance of HBsAg in Chronic Hepatitis B Patients with High HBsAg Levels. Gastroenterology 2023;164:669-679.
    3. Tseng TC, Hosaka T, Liu CJ, et al. Hepatitis B Core-Related Antigen Stratifies the Risk of Liver Cancer in HBeAg-Negative Patients With Indeterminate Phase. American Journal of Gastroenterology 2022;117:748-757.
    4. Tseng TC, Peng CY, Hsu YC, et al. Baseline Mac-2 Binding Protein Glycosylation Isomer Level Stratifies Risks of Hepatocellular Carcinoma in Chronic Hepatitis B Patients with Oral Antiviral Therapy. Liver Cancer 2020;9:207-220.
    5. Tseng TC, Liu CJ, Chang CT, et al. HEV superinfection accelerates disease progression in patients with chronic HBV infection and increases mortality in those with cirrhosis. J Hepatol 2020;72:1105-1111.
    6. Tseng TC, Liu CJ, Hsu CY, et al. High Level of Hepatitis B Core-Related Antigen Associated With Increased Risk of Hepatocellular Carcinoma in Patients With Chronic HBV Infection of Intermediate Viral Load. Gastroenterology 2019;157:1518-1529 e1513.
    7. Tseng TC, Liu CJ, Su TH, et al. Fibrosis-4 Index Helps Identify HBV Carriers With the Lowest Risk of Hepatocellular Carcinoma. Am J Gastroenterol 2017;112:1564-1574.
    8. Tseng TC, Liu CJ, Yang HC, et al. Higher proportion of viral basal core promoter mutant increases the risk of liver cirrhosis in hepatitis B carriers. Gut 2015;64:292-302.
    9. Tseng TC, Liu CJ, Yang HC, et al. Serum hepatitis B surface antigen levels help predict disease progression in patients with low hepatitis B virus loads. Hepatology 2013;57:441-450.
    10. Tseng TC, Liu CJ, Yang HC, et al. High levels of hepatitis B surface antigen increase risk of hepatocellular carcinoma in patients with low HBV load. Gastroenterology 2012;142:1140-1149. .
    11. Tseng TC, Liu CJ, Yang HC, et al. Determinants of spontaneous surface antigen loss in hepatitis B e antigen-negative patients with a low viral load. Hepatology 2012;55:68-76.
    12. Tseng TC, Liu CJ, Su TH, et al. Serum hepatitis B surface antigen levels predict surface antigen loss in hepatitis B e antigen seroconverters. Gastroenterology 2011;141:517-525 e512.