Chian-Fu ChenProfessor

Professor Chian-Fu Chen is a Distinguished Professor at the Institute of Applied Mechanics, National Taiwan University, and also serves as the Director of the NTU Nano-Electro-Mechanical Systems (NEMS) Research Center. His research interests and expertise encompass precision mechanical processing for biochemical detection and materials science applications, portable medical diagnostic systems, and the application of nanotechnology in environmental monitoring and medical fields. Additionally, Professor Chen has devoted significant effort to developing reagent analysis devices for advanced semiconductor processing. With extensive research experience in semiconductor fabrication and medical applications, Professor Chen has published his work in numerous prestigious academic journals. His applied research has also been recognized with the Future Technology Award from the National Science and Technology Council and a Fellowship from the Royal Society of Chemistry.

  • Publications 
        1. Chien, Y.-S., Tsai, T.-T., Lin, J.-H., Chang, C.-C., & Chen, C.-F. (2024). One-step copper deposition-induced signal amplification for multiplex bacterial infection diagnosis on a lateral flow immunoassay device. Biosensors and Bioelectronics, 267, 116849–116849. https://doi.org/10.1016/j.bios.2024.116849
        2. Tung, C.-Y., Tsai, T.-T., Chiu, P.-Y., Viter, R., Ramanavičius, A., Yu, C.-J., & Chen, C.-F. (2024). Diagnosis of Mycobacterium tuberculosis using palladium–platinum bimetallic nanoparticles combined with paper-based analytical devices. Nanoscale, 16(12), 5988–5998. https://doi.org/10.1039/d3nr05508f
        3. Chen, W.-T., Yan, C.-F., Yu, C.-J., Liao, Y.-C., & Chen, C.-F. (2024). Highly catalytic Prussian blue analogues and their application on the three-dimensional origami paper-based sweat sensors. Biosensors & Bioelectronics/Biosensors & Bioelectronics (Online), 254, 116188–116188. https://doi.org/10.1016/j.bios.2024.116188
        4. Chiou, Y., Pang, H., Huang, Y., & Chen, C. (2023). A Semi‐Automatic Environmental Monitoring Device for Mercury and Cobalt Ion Detection. Small, 20(8). https://doi.org/10.1002/smll.202303871
        5. Pilvenyte, G., Ratautaitė, V., Raimonda Boguzaite, Simonas Ramanavičius, Chen, C.-M., Viter, R., & Arūnas Ramanavičius. (2023). Molecularly Imprinted Polymer-Based Electrochemical Sensors for the Diagnosis of Infectious Diseases. Biosensors, 13(6), 620–620. https://doi.org/10.3390/bios13060620
        6. Chen, W.-T., Chiu, P.-Y., & Chen, C.-F. (2023). A flash signal amplification approach for ultrasensitive and rapid detection of single nucleotide polymorphisms in tuberculosis. Biosensors and Bioelectronics, 237, 115514–115514. https://doi.org/10.1016/j.bios.2023.115514
        7. Chu, W.-Y., Chiou, Y.-R., Luo, R.-H., Chen, T.-H., Yu, C.-J., Chou, Y.-J., Chang, H.-T., & Chen, C.-F. (2023). Partially miscible droplet microfluidics to enhance interfacial adsorption of hydrophilic nanoparticles for colloidosome synthesis. Chemical Engineering Journal, 471, 144223–144223. https://doi.org/10.1016/j.cej.2023.144223
        8. Liao, Y.-M., Chiu, P.-Y., Chien, Y.-S., & Chen, C.-F. (2023). Music Box-Inspired Semi-Automatic Hematocrit Validation Device. ACS Sensors, 8(8), 2952–2959. https://doi.org/10.1021/acssensors.3c00129
        9. Drobysh, M., Ramanaviciene, A., Viter, R., Chen, C.-F., Samukaite-Bubniene, U., Ratautaite, V., & Ramanavicius, A. (2022). Biosensors for the Determination of SARS-CoV-2 Virus and Diagnosis of COVID-19 Infection. International Journal of Molecular Sciences, 23(2), 666. https://doi.org/10.3390/ijms23020666
        10. Maryia Drobysh, Viktorija Liustrovaite, Ausra Baradoke, Viter, R., Chen, C.-F., Arunas Ramanavicius, & Arunas Ramanavicius. (2022). Determination of rSpike Protein by Specific Antibodies with Screen-Printed Carbon Electrode Modified by Electrodeposited Gold Nanostructures. 12(8), 593–593. https://doi.org/10.3390/bios12080593
        11. Chu, W.-Y., Yang, C.-H., Viter, R., Arũnas Ramanavičius, Luo, S.-C., & Chen, C.-F. (2022). Monolith-modified cellulose paper for biochemical sensing applications. Sensors & Diagnostics, 1(5), 994–1002. https://doi.org/10.1039/d2sd00108j
        12. Wu, S., Tsai, T.-T., Li, T.-H., Dung, C.-Y., Chiu, P.-Y., Lin, J.-H., & Chen, C.-F. (2022). Palladium-platinum bimetallic nanomaterials and their application in Staphylococcus aureus detection on paper-based devices. Biosensors and Bioelectronics, 216, 114669–114669. https://doi.org/10.1016/j.bios.2022.114669
        13. Chen, C.-A., Yuan, H., Chen, C.-W., Chien, Y.-S., Sheng, W.-H., & Chen, C.-F. (2021). An electricity- and instrument-free infectious disease sensor based on a 3D origami paper-based analytical device. Lab on a Chip, 21(10), 1908–1915. https://doi.org/10.1039/d1lc00079a
        14. Yuan, H., Tian, J., Chao, Y., Chien, Y.-S., Luo, R.-H., Guo, J.-Y., Li, S., Chou, Y.-J., Shum, H. C., & Chen, C.-F. (2021). Hand-Powered Microfluidics for Parallel Droplet Digital Loop-Mediated Isothermal Amplification Assays. ACS Sensors, 6(8), 2868–2874. https://doi.org/10.1021/acssensors.1c00184
        15. Hao, Y., Chiu, P.-Y., & Chen, C.-F. (2021). Paper-based analytical devices for point-of-care blood tests. 15(4). https://doi.org/10.1063/5.0055601
        16. Poon, S. H. L., Wong, W. H. L., Lo, A. C. Y., Yuan, H., Chen, C.-F., Jhanji, V., Chan, Y. K., & Shih, K. C. (2021). A systematic review on advances in diagnostics for herpes simplex keratitis. Survey of Ophthalmology, 66(3), 514–530. https://doi.org/10.1016/j.survophthal.2020.09.008
        17. Lin, J.-H., Tsai, T.-T., Zeng, Q., Chang, C.-Y., Guo, J.-Y., Lin, C.-J., & Chen, C.-F. (2020). A Multifunctional Microfluidic Device for Blood Typing and Primary Screening of Blood Diseases. ACS Sensors, 5(10), 3082–3090. https://doi.org/10.1021/acssensors.0c00969
        18. Li Wen Hsu, Yu Hsuan Lin, Jun Yu Guo, Chien Fu Chen, Yi Ju Chou, & Yi Chun Yeh. (2020). Simultaneous Determination of l-Phenylalanine, Phenylethylamine, and Phenylacetic Acid Using Three-Color Whole-Cell Biosensors within a Microchannel Device. ACS Applied Bio Materials, 3(8), 5120–5125. https://doi.org/10.1021/acsabm.0c00590
        19. Chou, Y.-J., Hung, C.-Y., & Chen, C.-F. (2019). Formation of drops and rings in double-diffusive sedimentation. Journal of Fluid Mechanics, 884. https://doi.org/10.1017/jfm.2019.946
        20. Chen, C.-A., Yeh, W.-S., Tsai, T.-T., Li, Y.-D., & Chen, C.-F. (2019). Three-dimensional origami paper-based device for portable immunoassay applications. Lab on a Chip, 19(4), 598–607. https://doi.org/10.1039/c8lc01255e